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Avinza (Morphine Sulfate) Extended-Release Capsules
Avinza 120mg is a powerful opioid (narcotic) medication designed for the around-the-clock treatment of chronic, severe pain.1 Because it is an extended-release formula, it is intended for long-term management and is not for use as an “as-needed” pain reliever.
Proper Administration
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Dosing: Usually taken once per day. If you miss a dose, take it as soon as possible and wait 24 hours before your next dose.
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Easy Swallowing: If you have trouble swallowing capsules, you may open the capsule and sprinkle the beads onto a spoonful of applesauce. Swallow immediately without chewing.
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Warning: Never crush, chew, or dissolve the beads. Doing so releases a potentially fatal dose of morphine all at once.
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Transitioning: Stop all other 24-hour narcotic medications before starting Avinza.
Important Safety Warnings
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Respiratory Danger: Morphine can significantly slow or stop your breathing.2 The risk is highest when starting the medication or increasing the dose.
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Alcohol Interaction: Do not consume alcohol.3 Combining alcohol with Avinza can lead to a fatal overdose.4
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Addiction & Misuse: This medication is habit-forming.5 Misuse can lead to addiction, overdose, or death. Store it securely away from children and others.
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MAO Inhibitors: Do not use if you have taken an MAO inhibitor (e.g., phenelzine, selegiline) in the last 14 days.6
Before You Take This Medicine
Consult your doctor if you have a history of:
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Breathing Issues: Severe asthma, COPD, or sleep apnea.
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Digestive Problems: Stomach/intestinal blockages or paralytic ileus.7
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Organ Health: Liver, kidney, gallbladder, or thyroid disease.8
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Neurological: Head injuries, brain tumors, or seizures.
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Pregnancy: Use during pregnancy can cause life-threatening withdrawal in the newborn. Do not breastfeed while using Avinza.
Potential Side Effects
| Common Side Effects | Serious Symptoms (Seek Help) |
| Constipation, nausea, and stomach pain | Slow heart rate or shallow breathing |
| Dizziness, drowsiness, and headache | Chest pain or pounding heartbeats |
| Mild itching or anxiety | Extreme drowsiness or fainting |
| General tired feeling | Signs of Serotonin Syndrome (fever, twitching) |
Storage and Disposal
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Storage: Store at room temperature away from heat, moisture, and light.9
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Disposal: Do not keep leftover capsules. Flush unused medication down the toilet or use a community drug take-back program to prevent accidental ingestion by children or pets.




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