Ketanest S (Esketamine Hydrochloride) 5 mg/mL
Ketanest S 5mg contains Esketamine, the S(+)-enantiomer of ketamine. It is a rapid-acting general anesthetic and powerful analgesic used for the induction and maintenance of anesthesia. Ketanest S is approximately twice as potent as racemic ketamine, allowing for effective anesthesia with a lower total dose and potentially faster recovery times.
Product Specifications
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Active Ingredient: Esketamine Hydrochloride
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Concentration: 5 mg/mL
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Form: Injection solution (Injektionslösung)
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Manufacturer: Pfizer
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Packaging: 10 Ampules (5 mL each)
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Preservative Status: Preservative-free (Ohne Konservierungsmittel)
Clinical Indications
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Induction of General Anesthesia: Used to rapidly transition patients into an anesthetic state for surgical procedures.
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Maintenance of Anesthesia: Administered as repeated doses or continuous infusion, often in combination with a hypnotic agent.
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Analgesia in Emergency Medicine: Provides profound pain relief in trauma or emergency settings without significantly depressing respiratory function.
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Supplement to Regional Anesthesia: Used to provide additional sedation and pain relief during local or regional blocks.
Administration Guidelines
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Professional Administration Only: This medication must only be administered by qualified healthcare professionals (such as anesthesiologists) in clinical environments equipped for full resuscitative support.
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Routes of Administration: Primarily intended for Intravenous (IV) or Intramuscular (IM) use.
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Continuous Monitoring: Mandatory monitoring of cardiac function, oxygen saturation, and respiratory rate is required throughout the administration and the recovery period.
Critical Safety Information & Precautions
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Emergence Reactions: Similar to racemic ketamine, patients may experience vivid dreams or confusion during the recovery phase. A quiet, low-stimulus environment is recommended to minimize these occurrences.
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Cardiovascular Effects: Esketamine can increase heart rate and blood pressure; it should be used with extreme caution in patients with uncontrolled hypertension or heart disease.
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Respiratory Protection: While protective airway reflexes are typically maintained, high doses or rapid IV administration can lead to respiratory depression.
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Intracranial Pressure: Caution is advised for patients with head injuries or conditions associated with increased intracranial pressure.
Potential Side Effects
| Common Effects | Serious Symptoms (Seek Help) |
| Elevated heart rate & blood pressure | Severe respiratory depression or apnea |
| Enhanced muscle tone | Laryngospasm (vocal cord closure) |
| Diplopia (Double vision) | Prolonged delirium or agitation |
| Nausea and vomiting | Arrhythmia (Irregular heartbeat) |
Why Source Ketanest S (Pfizer)?
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Pharmaceutical Precision: As a Pfizer product, Ketanest S meets the highest global standards for purity, potency, and sterile manufacturing.
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Enhanced Potency: The esketamine formulation allows for lower dosing compared to standard ketamine, which may result in a more favorable side-effect profile.
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Secure Global Logistics: Our medical supplies are handled with professional care and shipped via discreet, secure channels to ensure they arrive in optimal condition.
Storage: Store at controlled room temperature, protected from light. Keep in a secure, locked location to prevent unauthorized access.




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