ketanest

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Ketanest S (Esketamine Hydrochloride) 5 mg/mL

Ketanest S 5mg contains Esketamine, the S(+)-enantiomer of ketamine. It is a rapid-acting general anesthetic and powerful analgesic used for the induction and maintenance of anesthesia. Ketanest S is approximately twice as potent as racemic ketamine, allowing for effective anesthesia with a lower total dose and potentially faster recovery times.

Product Specifications

  • Active Ingredient: Esketamine Hydrochloride

  • Concentration: 5 mg/mL

  • Form: Injection solution (Injektionslösung)

  • Manufacturer: Pfizer

  • Packaging: 10 Ampules (5 mL each)

  • Preservative Status: Preservative-free (Ohne Konservierungsmittel)

Clinical Indications

  • Induction of General Anesthesia: Used to rapidly transition patients into an anesthetic state for surgical procedures.

  • Maintenance of Anesthesia: Administered as repeated doses or continuous infusion, often in combination with a hypnotic agent.

  • Analgesia in Emergency Medicine: Provides profound pain relief in trauma or emergency settings without significantly depressing respiratory function.

  • Supplement to Regional Anesthesia: Used to provide additional sedation and pain relief during local or regional blocks.

Administration Guidelines

  • Professional Administration Only: This medication must only be administered by qualified healthcare professionals (such as anesthesiologists) in clinical environments equipped for full resuscitative support.

  • Routes of Administration: Primarily intended for Intravenous (IV) or Intramuscular (IM) use.

  • Continuous Monitoring: Mandatory monitoring of cardiac function, oxygen saturation, and respiratory rate is required throughout the administration and the recovery period.

Critical Safety Information & Precautions

  • Emergence Reactions: Similar to racemic ketamine, patients may experience vivid dreams or confusion during the recovery phase. A quiet, low-stimulus environment is recommended to minimize these occurrences.

  • Cardiovascular Effects: Esketamine can increase heart rate and blood pressure; it should be used with extreme caution in patients with uncontrolled hypertension or heart disease.

  • Respiratory Protection: While protective airway reflexes are typically maintained, high doses or rapid IV administration can lead to respiratory depression.

  • Intracranial Pressure: Caution is advised for patients with head injuries or conditions associated with increased intracranial pressure.

Potential Side Effects

Common Effects Serious Symptoms (Seek Help)
Elevated heart rate & blood pressure Severe respiratory depression or apnea
Enhanced muscle tone Laryngospasm (vocal cord closure)
Diplopia (Double vision) Prolonged delirium or agitation
Nausea and vomiting Arrhythmia (Irregular heartbeat)

Why Source Ketanest S (Pfizer)?

  • Pharmaceutical Precision: As a Pfizer product, Ketanest S meets the highest global standards for purity, potency, and sterile manufacturing.

  • Enhanced Potency: The esketamine formulation allows for lower dosing compared to standard ketamine, which may result in a more favorable side-effect profile.

  • Secure Global Logistics: Our medical supplies are handled with professional care and shipped via discreet, secure channels to ensure they arrive in optimal condition.


Storage: Store at controlled room temperature, protected from light. Keep in a secure, locked location to prevent unauthorized access.

ketanest

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